Initiating translation with D-amino acids

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Outwitting EF-Tu and the ribosome: translation with d-amino acids

Key components of the translational apparatus, i.e. ribosomes, elongation factor EF-Tu and most aminoacyl-tRNA synthetases, are stereoselective and prevent incorporation of d-amino acids (d-aa) into polypeptides. The rare appearance of d-aa in natural polypeptides arises from post-translational modifications or non-ribosomal synthesis. We introduce an in vitro translation system that enables si...

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D-amino acids trigger biofilm disassembly.

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Pyridoxal enzymes acting on D-amino acids

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D-amino acids in animal peptides.

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ژورنال

عنوان ژورنال: RNA

سال: 2008

ISSN: 1355-8382

DOI: 10.1261/rna.1020708